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← Longevity dashboard

Longevity news

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100 relevant articles · classified by Haiku 4.5 · ingested daily

Jan 6Researchpositive
Shingles vaccine linked to lower dementia risk
A large analysis of NHS health records suggests the live shingles vaccine Zostavax may reduce dementia risk, using age-based eligibility as a natural experiment.
Longevity.Technology
Jan 6Research

Editorial analysis, not financial advice.

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© 2026 fobi

Editorial analysis, not financial advice.·FAQ

·positive

2025 Year in Review

NewLimit reports discovery of 30+ reprogramming payloads that restore youthful function in old cells and advances its AI-driven drug discovery platform.

NewLimit (official) ↗

Jan 5·Opinion·positive

Why LongBio is poised for a breakout at JPM 2026

Longevity biotech is entering mainstream investment era as the sector matures from aspiration to translational science and credible companies.

Longevity.Technology ↗

Jan 5·Research·neutral

New mitochondrial ‘uncouplers’ aim to raise energy burn safely

Researchers at UTS and Memorial University publish a study on engineered mitochondrial uncouplers designed to boost cellular energy expenditure without the safety risks of historical compounds like DNP.

Longevity.Technology ↗

Jan 2·Research·positive

First human trial links fasting mimicking diet to cellular renewal

Pilot clinical trial demonstrates that a five-day fasting-mimicking diet activates autophagy and improves metabolic markers in humans.

Longevity.Technology ↗

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Jan 2Researchpositive
NEJM publishes Phase 1/2 study of Denali’s tividenofusp alfa in Hunter syndrome
NEJM publishes Phase 1/2 results showing Denali's tividenofusp alfa reduced CNS and peripheral biomarkers in Hunter syndrome, with improved hearing and cognition.
Longevity.Technology
Jan 1Researchpositive
New Alzheimer’s research points to possible reversal
University Hospitals Cleveland Medical Center study shows NAD+ restoration reverses Alzheimer's-like damage in mouse models and human tissue.
Longevity.Technology
Jan 1Researchneutral
US obesity rate could soar under new definition
New study in JAMA Network Open finds waist-based obesity criteria could identify 75% of US adults as obese, double current BMI-based estimates.
Longevity.Technology
Dec 31Fundingpositive
Insilico bets on China to scale AI-led drug discovery
Insilico Medicine raises $293M in Hong Kong IPO with cornerstone backing from Eli Lilly, Schroders, Tencent, and Temasek.
Longevity.Technology
Dec 31Researchpositive
Tracking isn’t the breakthrough – prediction is
Mount Sinai researchers develop digital-twin models combining wearables and biomarkers to detect early physiological drift and predict disease onset.
Longevity.Technology
Dec 30Fundingpositive
Insilico debuts on HK Stock Exchange, locking in more than $290m
Insilico Medicine goes public on the Hong Kong Stock Exchange, raising $293m in an oversubscribed IPO, largest biotech IPO in Hong Kong this year.
Longevity.Technology
Dec 30Researchpositive
Retro Bio commences first-in-human trial
Retro Biosciences doses the first participant in a Phase 1 trial of RTR242, an autophagy-enhancing therapy targeting Alzheimer's disease.
Longevity.Technology
Dec 30Researchpositive
AI tool maps the heart to speed up drug discovery
CardioKG, an AI tool mapping heart imaging to genetic risk, published in Nature, accelerates cardiovascular drug discovery using data from 9,500 UK Biobank patients.
Longevity.Technology
Dec 30Demopositive
TruDiagnostic tops consumer at-home aging test list
Consumer365 names TruDiagnostic's TruAge Test the top at-home biological age test for 2026.
Longevity.Technology
Dec 29Researchneutral
Ancient genes may hold a modern key to longevity
Research in GeroScience links ancestral hunter-gatherer DNA patterns to increased longevity in Italian centenarians, analyzed via genomic comparison of 333 centenarians and 690 adults.
Longevity.Technology
Dec 26Researchpositive
Nanotherapy opens new avenue in Alzheimer’s treatment
A multi-target nanoparticle therapy improves neuron survival in Alzheimer's models from 40–50% to 90% by simultaneously targeting protein accumulation, inflammation, and neuronal damage.
Longevity.Technology
Dec 26Researchpositive
3D human genome maps advance disease research
Northwestern and the 4D Nucleome Project map 3D genome structure in stem cells to understand how DNA folding regulates genes and disease risk.
Longevity.Technology
Dec 25Researchpositive
Study links cholesterol drugs to slower Alzheimer’s decline
Swedish registry study of 15,586 Alzheimer's patients finds statin use associates with slower cognitive decline over three years.
Longevity.Technology
Dec 25Researchpositive
Brain enzyme tied to aging reveals drug opportunity
SIRT6 enzyme identified as a regulator of brain tryptophan metabolism, revealing a potential drug target for neurodegenerative disease and aging-related cognitive decline.
Longevity.Technology
Dec 24Partnershippositive
The year longevity stopped being theoretical
Gero's AI aging-models platform partners with Chugai Pharmaceutical as longevity field shifts from theory to clinical practice in 2025.
Longevity.Technology
Dec 23Researchpositive
Mitochondrial architecture and longevity
Elevated COX7RP expression boosts mitochondrial supercomplex assembly, improving metabolic health and extending lifespan in transgenic mice.
Longevity.Technology
Dec 22Opinionneutral
Is your longevity startup accidentally a healthcare provider?
Longevity startups navigate a regulatory gray zone where wellness tech crosses into licensed healthcare, and product design choices can trigger compliance obligations.
Longevity.Technology
Dec 22Researchneutral
Facial lipid changes signal early skin aging
Lipidomics analysis of 151 Chinese women reveals measurable shifts in facial skin lipids begin in the 20s, signaling early-stage aging at the chemical level.
Longevity.Technology
Dec 19Fundingpositive
GlycanAge closes $8.7m to take glycan biomarkers into hospitals
GlycanAge closes $8.7M led by Fifth Quarter Ventures to expand glycan biomarker testing into hospitals and preventive-care systems.
Longevity.Technology
Dec 19Researchpositive
Urolithin A: The gut-made molecule that has scientists excited
A Nature-published study finds urolithin A improves immune aging biomarkers and muscle function in a 50-person trial over four weeks.
Longevity.Technology
Dec 18Launchpositive
Kenai Therapeutics doses first patient in Phase 1 neuron replacement Parkinson’s trial
Kenai Therapeutics doses first patient in Phase 1 trial of RNDP-001, an iPSC-derived neuron replacement therapy for Parkinson's disease.
Longevity.Technology
Dec 18Partnershippositive
UK–Singapore corridor to fast-track health tech
UK and Singapore establish a Regulatory Innovation Corridor enabling faster, coordinated health-tech approvals with Flagship Pioneering as first industry partner.
Longevity.Technology
Dec 17Fundingpositive
TauC3 Biologics advances neurodegenerative disease treatment
TauC3 Biologics secures $2.5M in commitments to extend runway and prepare a £25M Series A for first-in-human tau antibody trials.
Longevity.Technology
Dec 16Launchpositive
Hundred Health launches integrated proactive care platform
Hundred Health launches an integrated platform combining lab tests, wearables, and health records into personalized 100-day action plans for preventive care.
Longevity.Technology
Dec 16Fundingpositive
Aeovian lands $55m to advance pipeline focused on mTOR biology
Aeovian Pharmaceuticals closes a $55M Series B led by Luma Group to advance mTORC1 inhibitor AV078 for epilepsy and age-related conditions.
Longevity.Technology
Dec 16Fundingpositive
Cellular Origins lands $40m to scale cell therapies
Cellular Origins raises $40M Series A, led by J&J Innovation, to automate cell-therapy manufacturing for age-related conditions.
Longevity.Technology
Dec 15Launchpositive
Noom launches longevity-focused GLP-1 program
Noom launches a preventive health program combining microdosed GLP-1 medications, biomarker monitoring, and digital behavior-change coaching targeting metabolic disease risk.
Longevity.Technology
Dec 15Researchpositive
Dark chocolate and biological aging
Study links theobromine, a cocoa metabolite, to slower epigenetic aging in two human cohorts measured by DNA methylation clocks.
Longevity.Technology
Dec 12Fundingpositive
Can ‘physical AI’ help accelerate longevity drug development?
Medra closes $52M Series A for an AI-robotics platform designed to accelerate drug discovery through continuous experimentation cycles.
Longevity.Technology
Dec 12Researchpositive
Nanoflowers boost mitochondrial handovers in cells
Texas A&M researchers use engineered MoS₂ nanoflowers to boost mitochondrial transfer between stem cells, doubling donor mitochondrial mass in a PNAS study.
Longevity.Technology
Dec 11Opinionneutral
‘We are focusing the future GSK around prevention’
GSK Chair Jonathan Symonds discusses the pharma industry's shift toward prevention and healthspan in the context of Hevolution's Global Healthspan Report.
Longevity.Technology
Dec 11Regulationpositive
UK secures 0% drug tariffs in landmark US deal
UK secures 0% tariffs on pharmaceutical exports to the US, removing trade barriers for drug development including longevity therapies.
Longevity.Technology
Dec 10Partnershippositive
Artrya’s heart disease AI cloud platform expands in US
Artrya's Salix AI platform for cardiovascular assessment launches at Northeast Georgia Health System covering 100,000+ patients annually.
Longevity.Technology
Dec 10Partnershippositive
Ultimate Longevity Center combines fitness and prevention under one roof
Lifeforce partners with Sequel Brands and biohacker Gary Brecka to launch Ultimate Longevity Center, integrating clinical longevity medicine with fitness and performance services.
Longevity.Technology
Dec 9Researchpositive
Bone-targeted estrogen reverses bone loss in mice
Researchers at East China University and Sichuan University develop a bone-targeted estradiol nanocarrier that reverses osteoporotic bone loss in mice without uterine side effects.
Longevity.Technology
Dec 8Researchpositive
Synaptic regeneration treatment delivers positive Alzheimer’s trial data
Spinogenix reports Phase 2a trial of tazbentetol shows early, sustained cognitive improvement in Alzheimer's patients.
Longevity.Technology
Dec 8Researchpositive
New cancer drug shows surprising antiaging effects
Queen Mary University of London researchers find that rapalink-1, a TOR inhibitor, extends lifespan in fission yeast through metabolic feedback loops, suggesting oncology drugs may have longevity applications.
Longevity.Technology
Dec 5Fundingpositive
Therapeutic plasma exchange startup lands strategic investment
Circulate Health, a therapeutic plasma exchange startup, secures a seven-figure strategic investment from Scrum Ventures to expand clinical research and its network of longevity clinics.
Longevity.Technology
Dec 5Researchpositive
BioAge shows promise with new drug BGE-102 in early trial
BioAge Labs reports encouraging Phase 1 data for BGE-102, an NLRP3 inhibitor with brain penetration, and expands trial enrollment to obesity and inflammation populations.
Longevity.Technology
Dec 5Researchpositive
Turning gut bacteria into longevity factories
Scientists at Howard Hughes Medical Institute reprogram gut bacteria with low-dose antibiotics to overproduce longevity-linked compounds, extending lifespan in worms and improving metabolic health in mice.
Longevity.Technology
Dec 4Partnershippositive
Longevity.Technology and IIOL form industry standards alliance
Longevity.Technology and the International Institute for Longevity partner to establish clinical standards and transparency across the longevity-clinic ecosystem.
Longevity.Technology
Dec 4Researchpositive
Swapping the way to neural resilience
Microglia replacement therapy halts disease progression in adult-onset leukoencephalopathy patients, advancing from mouse models to human clinical use in five years.
Longevity.Technology
Dec 3Researchneutral
The hidden fat sabotaging your brain and how muscle helps
MRI study of 1,164 adults finds visceral fat accelerates brain aging while muscle mass slows it, with AI brain-age estimation revealing inflammation mechanisms.
Longevity.Technology
Dec 3Demopositive
Fountain Life brings $20m ROI with preventive healthcare
Fountain Life reports a 13:1 return on investment and 80% health optimization in its Executive Health Membership Program using AI imaging and biomarker analytics.
Longevity.Technology
Dec 3Fundingpositive
Junevity lands more funding for siRNA-powered cellular reprogramming
Junevity doubles seed funding to $20M for siRNA-based cellular reprogramming therapy targeting type 2 diabetes and obesity.
Longevity.Technology
Dec 2Researchpositive
Healthspan gains momentum in new global report
Hevolution Foundation publishes its second Global Healthspan Report, documenting rising public interest, scientific progress, and investment doubling across 23 countries.
Longevity.Technology
Dec 2Fundingpositive
Circular Genomics lands $15m to detect Alzheimer’s via ‘circular RNA’
Circular Genomics secures $15M Series A to develop circRNA-based diagnostics for early Alzheimer's detection.
Longevity.Technology
Dec 2Researchpositive
$30k NADMED award to advance metabolomics research
NADMED launches a $30k research award to fund metabolomics studies of redox metabolism and cellular aging.
Longevity.Technology
Dec 2Researchpositive
Vandria moves Alzheimer’s candidate forward after Phase 1 signal
Vandria's VNA-318 shows biomarker engagement and clean safety in Phase 1 for mild cognitive impairment, clearing a key hurdle for its novel mitochondrial-inflammation target.
Longevity.Technology
Dec 2Researchneutral
New studies tie social support to longevity of older adults
University of Eastern Finland research links strong social support networks to extended lifespan and improved well-being in older adults, with a two-year longevity advantage observed.
Longevity.Technology
Dec 1Otherneutral
Navigating the global longevity clinics boom
Survey of 82 longevity clinics globally reveals consumer demand for preventive health and diagnostics, with mixed science grounding and aesthetic service offerings.
Longevity.Technology
Dec 1Researchpositive
Hidden blood molecules hint at new paths to skin-aging therapies
Researchers identify blood-derived bacterial metabolites that reduce inflammation and collagen breakdown in skin-aging models.
Longevity.Technology
Nov 28Partnershippositive
Insurance giant launches $350m longevity institute
Manulife commits $350M through 2030 to a Longevity Institute for research and advocacy on healthspan and financial resilience.
Longevity.Technology
Nov 28Researchneutral
New map reveals five eras of brain aging
Research mapping five distinct eras of brain aging from birth to age 83 in 3,800+ brain scans identifies neural turning points at ages 9, 32, 66, and 83.
Longevity.Technology
Nov 27Researchneutral
Why we age is still longevity’s biggest question
A peer-reviewed roadmap in Geroscience identifies 100 open problems in aging science to guide biogerontology research priorities.
Longevity.Technology
Nov 27Researchpositive
NewLimit ‘close’ to clinic-ready epigenetic reprogramming therapy
NewLimit advances its epigenetic reprogramming therapy toward human clinical trials, with a liver-targeted lead candidate demonstrating youthful cell function restoration.
Longevity.Technology
Nov 27Researchpositive
Patent filed for Immorta Bio’s new senolytic vaccine
Immorta Bio publishes patent for SenoVax, a senolytic immunotherapy designed to eliminate senescent cells and potentially reduce tumor growth in preclinical studies.
Longevity.Technology
Nov 27Researchpositive
Psyence BioMed leads longevity research on psilocybin
Psyence BioMed launches a research program investigating psilocybin's effects on biological aging markers and healthspan.
Longevity.Technology
Nov 26Partnershippositive
Novo Nordisk backs biotech start-up targeting aging
General Control emerges from stealth to partner with Novo Nordisk's Co-Creation Greenhouse on programmable epigenetic editing for aging-related diseases.
Longevity.Technology
Nov 26Fundingpositive
Biotech lands funding to combat Alzheimer’s by targeting the immune system
MindImmune Therapeutics raises $30 million in Series A funding to advance Phase 1 trials of an immune-targeted Alzheimer's drug.
Longevity.Technology
Nov 26Researchneutral
Hormones shape frailty risk in aging dogs
Study of 87 geriatric Rottweilers links early endocrine disruption to late-life frailty severity, suggesting hormonal context shapes aging outcomes.
Longevity.Technology
Nov 26Researchpositive
Brain Age Gap predicts cognitive decline risks
Vision Transformer model predicts brain age with 2.7–3.2 year precision, linking accelerated aging to Alzheimer's, cognitive decline, and mortality risk.
Longevity.Technology
Nov 25Partnershippositive
New deal to develop therapy targeting deadly heart risk
Repair Biotechnologies partners with AGC Biologics to develop an mRNA therapy targeting atherosclerosis-driven heart attack and stroke risk.
Longevity.Technology
Nov 25Researchneutral
Mapping the unanswered questions of aging
A paper in GeroScience identifies 100 open problems in aging biology to guide future research directions in the field.
Longevity.Technology
Nov 25Launchpositive
NAD+ pioneer debuts new beauty supplement
Niagen Bioscience launches Tru Niagen Beauty, pairing its patented NAD+ precursor with skin and hair ingredients.
Longevity.Technology
Nov 24Researchpositive
Aging biomarker science widens its scope
The Biomarkers of Aging Conference convenes researchers, clinicians, and biotech leaders to advance biological-age measurement tools toward clinical adoption.
Longevity.Technology
Nov 24Researchpositive
September // October 2025 Progress Update
NewLimit reports advances in epigenetic reprogramming therapeutics for hepatocyte rejuvenation, with lead candidate 8X more specific than prior prototype.
NewLimit (official)
Nov 21Researchneutral
When the system stops trying
Researchers propose aging as loss of biological goal-directedness, a systems-level theory distinct from molecular damage models.
Longevity.Technology
Nov 21Launchpositive
Startup introduces multi-organ biological age test for women
BASE4 Biosciences launches a blood-based multi-organ biological age test built on AI models trained exclusively on female biological data.
Longevity.Technology
Nov 21Otherneutral
Full-body MRI: early insights for longer, healthier living
Full-body MRI scans are increasingly used in longevity clinics as a radiation-free baseline for early disease detection and preventive health tracking.
Longevity.Technology
Nov 20Fundingpositive
Preventive health disruptor hits $2.5 billion valuation
Function Health closes $298M Series B at $2.5B valuation, expands biomarker testing platform with AI-driven medical intelligence.
Longevity.Technology
Nov 20Researchneutral
Can genetic medicine solve cardiovascular disease?
Scribe Therapeutics explores next-generation CRISPR systems to address atherosclerotic cardiovascular disease and other chronic conditions affecting global longevity.
Longevity.Technology
Nov 19Fundingpositive
Mitophagy-promoting Parkinson’s drug funded into clinical trials
Vincere Biosciences secures $5M Michael J. Fox Foundation grant to advance USP30 inhibitor into Phase 1 trials for Parkinson's disease.
Longevity.Technology
Nov 19Regulationnegative
When longevity research hits a fiscal headwind
Proposed 40% NIH budget cuts create uncertainty for geroscience research funding and career planning, though Congress signals resistance to deep austerity.
Longevity.Technology
Nov 18Fundingpositive
Startup emerges with $8m to combat musculoskeletal diseases
Skeletalis raises $8M to develop bone-targeted small molecules for osteoporosis treatment.
Longevity.Technology
Nov 18Researchneutral
Aging spleens and faltering T cells
Research from Technion-Israel Institute reveals that aged splenic microenvironment impairs T-cell function, pointing to new targets for immune rejuvenation.
Longevity.Technology
Nov 18Researchneutral
Six genes reveal aging’s hidden drivers
Researchers identify six genes that drive aging across species, extending C. elegans lifespan 8–15% when inhibited.
Longevity.Technology
Nov 17Fundingpositive
Startup aims to ‘change the script’ on age-related diseases
Scripta Therapeutics emerges from stealth with $12M in seed funding to develop transcription-factor-targeting therapeutics for neurodegeneration.
Longevity.Technology
Nov 17M&Anegative
AbbVie parts ways with Calico
AbbVie ends its 11-year partnership with Calico Labs after limited clinical success, affecting ~100 staff; Calico's ALS candidate fosigotifator failed endpoints.
Longevity.Technology
Nov 14Otherpositive
Army of AI agents joins the longevity race
Hackaging.ai global hackathon unites 966 participants from 26 countries to develop AI tools for longevity, with Retro Biosciences and Gero among 11 sponsors.
Longevity.Technology
Nov 14Researchpositive
NAD+ boost shows promise in Long COVID study
Niagen Bioscience-funded trial shows nicotinamide riboside improves fatigue and sleep in Long COVID patients; results published in eClinicalMedicine.
Longevity.Technology
Nov 12Opinionneutral
Agentic AI: The new frontier of precision longevity
Agentic AI could integrate fragmented longevity data to enable adaptive, personalized health guidance rather than static reports.
Longevity.Technology
Nov 11Partnershippositive
Insilico and Lilly deepen AI drug discovery alliance
Insilico Medicine and Eli Lilly expand their AI drug discovery partnership with potential deal value exceeding $100M including upfront, milestones, and royalties.
Longevity.Technology
Nov 11Researchpositive
Klotho, neuroprotection and the biology of aging
Klotho Neurosciences advances gene therapy targeting Klotho protein to protect neurons in ALS, building on foundational aging biology.
Longevity.Technology
Nov 11Partnershippositive
Neurotech firm inks AI partnership with Microsoft
Inbrain Neuroelectronics partners with Microsoft to integrate agentic AI into graphene-based BCIs for real-time neural adaptation in Parkinson's and cognitive decline treatment.
Longevity.Technology
Nov 10Opinionnegative
When AI cures – and counterfeits
Deepfake videos impersonating longevity researcher David Sinclair spread false health claims, raising risks of AI-driven medical misinformation.
Longevity.Technology
Nov 10Researchpositive
Danish biotech kicks off first-in-human Alzheimer’s trial
Muna Therapeutics doses first participants in a Phase 1 trial of MNA-001, a TREM2 agonist targeting Alzheimer's via brain resilience mechanisms.
Longevity.Technology
Nov 7Otherneutral
Longevity clinics converge to shape sector’s future
The Third Roundtable of Longevity Clinics convenes leading practitioners and researchers to advance standards and collaboration in longevity medicine, featuring speakers on aging biology and practitioners from sector clinics.
Longevity.Technology
Nov 7Regulationpositive
Texas voters approve $3bn brain health research bill
Texas voters approve $3B in state funding for neurodegenerative disease research and brain health over the next decade via Proposition 14.
Longevity.Technology
Nov 7Launchpositive
Insilico expands AI reach into metabolic health
Insilico Medicine unveils eight cardiometabolic drug candidates discovered via its Pharma.AI platform, targeting inflammation, insulin sensitivity, and energy metabolism.
Longevity.Technology
Nov 5Otherneutral
Measuring, reversing and rethinking aging
The 6th TimePie Longevity Forum in Shanghai convened 1,500 participants to discuss advances in aging science, biological clocks, and AI-guided drug discovery.
Longevity.Technology
Nov 4Researchneutral
Naked mole-rat’s DNA repair secret revealed
Researchers at Tongji University identify four amino acid mutations in naked mole-rat cGAS that enhance DNA repair and slow aging, published in Science.
Longevity.Technology
Nov 3Partnershippositive
Nautilus and the Buck harness proteomics in aging research
Nautilus Biotechnology and the Buck Institute deploy a single-molecule proteomics platform for six months to study tau protein modifications in Alzheimer's research.
Longevity.Technology
Oct 31Launchpositive
mTOR science has skin in the game
Rapalogix Health, a Cambrian Bio spinout, launches Re-Q, a physician-dispensed skincare line featuring an mTORC1-selective inhibitor targeting cellular aging.
Longevity.Technology
Oct 30Fundingpositive
Former Altos scientists launch women’s health biotech
Cyclana Bio, founded by former Altos Labs scientists, raises $6.6M pre-seed for endometriosis therapeutics using tissue-modeling technology.
Longevity.Technology

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