Periodic Labs builds AI scientists paired with autonomous robotic laboratories to discover new materials, starting with higher-temperature superconductors.

AI Materials Discovery · Seed $300M

AI Materials Discovery

Seed

$300M

HQ

CuspAI is building an AI-native 'search engine' for materials that designs novel compounds to match a target set of physical properties.

AI Materials Discovery · Series A $100M

AI Materials Discovery

Series A

$100M

HQ

Cyclic Materials recycles rare earth elements and other critical metals from end-of-life magnets, motors, EVs and e-waste to build a circular supply chain.

Critical Minerals & Mining Tech · Series C $75M

Critical Minerals & Mining Tech

Series C

$75M

HQ

MIT spinout decarbonizing steel and critical-metals production with molten oxide electrolysis (MOE) powered by renewable electricity.

Advanced Metals & Metallurgy · Growth (critical metals) $75M

Advanced Metals & Metallurgy

Growth (critical metals)

$75M

HQ

Oakland startup producing carbon-neutral magnesium metal by electrolysis of seawater and brines to rebuild U.S. magnesium supply.

Advanced Metals & Metallurgy · Series A $24M

Advanced Metals & Metallurgy

Series A

$24M

HQ

Paragraf mass-produces graphene-based electronic devices, including Hall-effect sensors and transistors, on standard semiconductor manufacturing lines.

Nanomaterials & Carbon · Series C $55M

Nanomaterials & Carbon

Series C

$55M

HQ

Xampla makes plastic-free, biodegradable materials from plant protein to replace single-use plastics, films, coatings and microplastics.

Specialty Polymers, Coatings & Surfaces · Series A $14M

Specialty Polymers, Coatings & Surfaces

Series A

$14M

HQ

Orbital Industries uses an AI atomic-simulation engine to discover novel materials, starting with PFAS-free dielectric coolants for high-density GPUs.

AI Materials Discovery · Series B $50M

AI Materials Discovery

Series B

$50M

HQ

Aqua Metals recovers high-purity battery metals from spent lithium-ion batteries using its room-temperature, electrochemical AquaRefining process.

Advanced Metals & Metallurgy · Market cap $9.0M

Advanced Metals & Metallurgy

Market cap

$9.0M

HQ

KoBold Metals uses AI and machine learning to explore for critical minerals like copper, lithium, cobalt and nickel needed for batteries and electrification.

Sila Nanotechnologies engineers silicon-dominant anode materials that replace graphite to boost lithium-ion battery energy density.

Boulder startup making fossil-free iron with a low-temperature electrochemical process that turns low-grade ore into 99% pure iron using renewable electricity.

Advanced Metals & Metallurgy · Series B $186M

Advanced Metals & Metallurgy

Series B

$186M

HQ

Arris Composites uses its Additive Molding process to align continuous carbon fiber inside thermoplastics, mass-producing high-performance structural parts.

San Jose supermaterials company using 3D Graphene to build lithium-sulfur batteries, lightweight composites and sensors, now scaling via acquired Northvolt assets.

Nanomaterials & Carbon · Strategic investment $200M

Nanomaterials & Carbon

Strategic investment

$200M

HQ

Woburn-based refiner producing rare-earth and critical metals from mining tailings and scrap with a zero-waste, net-zero process.

Advanced Metals & Metallurgy · Series B $76M

Advanced Metals & Metallurgy

Series B

$76M

HQ

Lilac Solutions uses an ion-exchange direct lithium extraction technology to pull lithium from brines with high recovery and low cost.

Fairmat recycles carbon-fiber composite waste into engineered chips that are reassembled into new high-performance composite parts.

Advanced Composites & Manufacturing · Series B $56M

Advanced Composites & Manufacturing

Series B

$56M

HQ

Radical AI builds an autonomous, self-driving materials lab that unifies machine learning, robotic synthesis, and characterization to discover and make advanced materials.

AI Materials Discovery · Seed $55M

AI Materials Discovery

Seed

$55M

HQ

Mangrove Lithium uses a proprietary electrochemical process to refine lithium feedstocks into battery-grade lithium hydroxide and carbonate.

Critical Minerals & Mining Tech · Series B $35M

Critical Minerals & Mining Tech

Series B

$35M

HQ

Aether Diamonds grows carbon-negative lab diamonds from CO2 captured out of the atmosphere.

Chemix uses its MIX generative-AI platform to design custom battery chemistries and electrolyte formulations from large proprietary experimental datasets.

AI Materials Discovery · Series A $20M

AI Materials Discovery

Series A

$20M

HQ

Mattiq combines combinatorial nanomaterials synthesis with AI to rapidly discover catalysts for cleaner chemicals and fuels.

AI Materials Discovery · Seed $15M

AI Materials Discovery

Seed

$15M

HQ

Actnano makes fluorine-free conformal nanocoatings that protect automotive and consumer electronics from moisture and corrosion.

Citrine Informatics offers an AI platform that helps materials and chemicals companies design and optimize new products from their R&D data.

AI Materials Discovery · Series B $20M

AI Materials Discovery

Series B

$20M

HQ

Boston startup turning scrap aluminum into clean hydrogen and heat with activated-aluminum reactors for heavy industry.

Advanced Metals & Metallurgy · Seed $12M

Advanced Metals & Metallurgy

Seed

$12M

HQ

Novoloop chemically upcycles post-consumer polyethylene waste into high-performance, low-carbon thermoplastic polyurethanes.

Los Alamos nanotech company making low-toxicity quantum dots for greenhouse lighting, solar windows and security applications.

Nanomaterials & Carbon · Series B $20M

Nanomaterials & Carbon

Series B

$20M

HQ

Adaptive Surface Technologies makes liquid-infused SLIPS coatings that repel fluids, contaminants, and biofouling.

Durin builds and operates remotely operated, semi-autonomous drill rigs to make mineral exploration faster, safer and cheaper.

Aionics runs a closed-loop AI platform that designs and screens battery electrolytes and chemical formulations, combining machine learning with physics-based simulation.

AI Materials Discovery

AI Materials Discovery

—

—

HQ

Dunia Innovations operates a self-driving lab that fuses AI, robotics, and simulation into a closed loop to discover catalysts, battery materials, and semiconductor materials.

AI Materials Discovery · Seed $11.5M

AI Materials Discovery

Seed

$11.5M

HQ

Earth AI pairs an AI mineral-targeting platform with its own low-disturbance drilling to find and validate clean-energy metal deposits in untapped ground.

Critical Minerals & Mining Tech · Series B $20M

Critical Minerals & Mining Tech

Series B

$20M

HQ

Boston company recovering critical metals from scrap, tailings and low-grade ore with a modular electro-extraction system using only electricity and carbon filters.

Advanced Metals & Metallurgy · Series B $44M

Advanced Metals & Metallurgy

Series B

$44M

HQ

Canadian materials company using Flash Joule Heating to upcycle waste carbon into bulk graphene at industrial scale.

Nanomaterials & Carbon · Equity $20M

Nanomaterials & Carbon

Equity

$20M

HQ

IperionX produces low-carbon titanium metal and powder in the US from recycled scrap and domestic ore using its patented HAMR and HSPT processes.

Advanced Metals & Metallurgy · Market cap $1.0B

Advanced Metals & Metallurgy

Market cap

$1.0B

HQ

Boston Materials makes Z-axis Fiber, vertically aligning carbon fiber to boost thermal management and lightweighting across semiconductors, aerospace and EVs.

Mallinda makes Vitrimax vitrimer resins that give composites thermoset strength while letting them be reshaped and fully recycled back to monomer.

Mango Materials ferments waste methane into biodegradable PHA biopolymers as drop-in replacements for petroleum plastics.

Bengaluru company producing high-purity single-walled carbon nanotubes at scale using the HiPCO process for batteries, electronics and quantum applications.

Nanomaterials & Carbon · Pre-Series A $3M

Nanomaterials & Carbon

Pre-Series A

$3M

HQ

NanoXplore is a publicly traded graphene producer operating one of the world's largest graphene manufacturing facilities and supplying graphene-enhanced plastics and composites.

Nanomaterials & Carbon · Market cap $205.9M

Nanomaterials & Carbon

Market cap

$205.9M

HQ