1
Seed
Biotech
Biotech
Biotech
Companies
- 01
Prime MedicinePrime-editing platform offering programmable 'search-and-replace' genome editing across many mutation types. - 02
Generate BiomedicinesGenerative-biology company using diffusion models to design novel protein therapeutics from scratch. - 03
Chai DiscoveryBuilds foundation models for biomolecular structure prediction and fully de novo antibody design. - 04
Beam TherapeuticsBase-editing platform that rewrites single DNA letters precisely, without making double-strand breaks. - 05
Mammoth BiosciencesEngineering-biology platform building ultra-compact CRISPR systems for in vivo gene editing and CRISPR-based diagnostics. - 06
Twist BioscienceManufactures synthetic DNA by writing it on a silicon chip, supplying genes, oligo pools, NGS tools, antibody libraries, and DNA data storage. - 07
ProfluentBuilds large language models for protein design and created OpenCRISPR-1, the first AI-generated gene editor. - 08
LanzaTechLanzaTech uses gas-fermenting bacteria to convert captured carbon and waste industrial gases into ethanol and other chemicals. - 09
Basecamp ResearchBuilds an ethically-sourced global biodiversity database, BaseData, to fuel generative protein foundation models. - 10
CradleGenerative-AI protein-engineering SaaS that lets any lab design and optimize proteins without deep computational expertise. - 11
BiomemoryDevelops enzymatic DNA data-storage technology, encoding digital information into synthetic DNA on a credit-card-sized medium for ultra-dense, long-lived archival storage. - 12
Ansa BiotechnologiesUses enzymatic synthesis to make long, sequence-perfect clonal DNA up to 50 kilobases, backed by an on-time delivery guarantee. - 13
Arbor BiotechnologiesProtein-discovery engine that finds and engineers novel compact CRISPR and editing enzymes for genetic medicines.
Tracked
AllonniaAllonnia engineers microbes and enzymes to break down pollutants and recover critical minerals from waste streams.
AntheiaAntheia uses engineered yeast fermentation to manufacture plant-inspired pharmaceutical ingredients such as thebaine without growing the source crops.
AsimovCAD-for-biology genetic design tools paired with engineered mammalian cell lines for therapeutics manufacturing.
Bota BiosciencesAI- and automation-driven strain-engineering biofoundry producing bio-based ingredients for food and personal care.
Caribou BiosciencesCRISPR genome-editing platform built on chRDNA hybrid guides for higher-precision, multiplexed edits.
CellaresAutomated 'Cell Shuttle' factories that industrialize and scale cell-therapy manufacturing.
CRISPR TherapeuticsCRISPR Therapeutics develops gene-editing medicines built on CRISPR/Cas9, including the approved cell therapy Casgevy and the investigational in vivo liver therapy CTX310, for patients with serious and cardiometabolic diseases.
Culture BiosciencesCloud bioreactors and Console software that let teams run and monitor bioprocess development experiments remotely.
ElegenBuilds long, accurate synthetic DNA in days using its cell-free, microfluidics-based ENFINIA DNA platform.
MetagenomiGenetic-medicines platform that mines metagenomic sequence data to build a broad, proprietary gene-editing toolbox.
NovonesisNovonesis, based in Bagsværd, Denmark, develops enzymes and microbial cultures for household care, bioethanol, and human health and food applications. Its customers include detergent makers, biorefinery operators, and food and supplement manufacturers.
Opentrons LabworksAffordable open-source liquid-handling lab robots that automate pipetting and other benchtop workflows.
RoeblingRoebling (formerly Synonym) builds software and financing infrastructure to plan, model, and fund biomanufacturing and other industrial process facilities.
Scribe TherapeuticsMolecular-engineering platform that builds CRISPR enzymes from the ground up and licenses them for in vivo gene editing.
Tessera TherapeuticsGene Writing platform using engineered mobile genetic elements to write everything from single bases to whole genes.
64x BioHigh-throughput cell-line engineering to boost yields for viral-vector and gene-therapy manufacturing.
A-Alpha BioA-Alpha Bio builds AI protein and enzyme design tools, including the AlphaBind model and the Atlas data ecosystem, for biopharma researchers and drug developers working on antibodies and therapeutic proteins.
ArzedaComputational de novo protein and enzyme design company spun out of David Baker's University of Washington lab.
BenchlingBenchling sells a cloud R&D platform where biotech scientists design sequences, record experiments, track samples and run AI agents and models, used by more than 1,300 companies including Merck, Moderna and Sanofi.
Capra BiosciencesCapra Biosciences uses a modular biofilm-reactor platform to make specialty chemicals like retinol from low-cost waste feedstocks.
CauldronCauldron is an Australian precision-fermentation company whose continuous 'hyper-fermentation' platform aims to boost yields and cut biomanufacturing costs.
Colossal BiosciencesColossal Biosciences uses genome editing, cloning and AI to recreate traits of extinct species such as the woolly mammoth, thylacine and dodo, and spins the tools it builds out into companies such as Form Bio and Breaking.
Constructive BioBuilds fully recoded synthetic genomes that reprogram the genetic code so engineered cells can produce proteins and biopolymers with chemistries natural biology cannot make.
DNA ScriptPioneers enzymatic DNA synthesis on the benchtop with SYNTAX, the first commercial enzymatic DNA printer, letting labs make oligos on demand.
Dyno TherapeuticsUses AI to engineer AAV capsids as improved gene-delivery vectors, licensing designs to major pharma.
Ginkgo BioworksHorizontal cell-programming foundry offering biological engineering as a service, plus AI data generation and biosecurity arms.
IntelliaIntellia Therapeutics develops one-time CRISPR gene-editing treatments delivered into the body in lipid nanoparticles, led by lonvo-z for hereditary angioedema and nex-z for transthyretin amyloidosis.
Isomorphic LabsIsomorphic Labs, a Google DeepMind spinout, uses AI models built on AlphaFold to design small-molecule and biologic drug candidates for its own pipeline and for partners Eli Lilly, Novartis and Johnson & Johnson.
LatchBioCloud bioinformatics platform for orchestrating and analyzing large biological datasets without code.
Pow.bioPow.bio offers continuous-fermentation technology and contract manufacturing (CDMO) services aimed at cutting the cost of biomanufactured products.
SolugenSolugen makes bio-based chemicals at its 'Bioforge' plants using a chemienzymatic process that pairs engineered enzymes with metal catalysts.
XairaXaira Therapeutics builds AI models for target discovery and de novo antibody design, linked to agentic AI and robotic lab automation, to develop its own pipeline of drug candidates.
No roster changes this week. The roster is re-evaluated quarterly; read the methodology in the disclosures.
