NeuroPace (NPCE) is a publicly traded Neuromodulation & Stimulation company founded in 1997 and based in Mountain View, United States.
| Date | Stage | Amount | Valuation | Lead investors |
|---|---|---|---|---|
| Apr 26, 2021 | IPO | $105.2M | — | — |
NeuroPace reported Q2 2026 revenue of $22.8 million, with RNS System revenue of $22.5 million representing 21.3% year-over-year growth. GAAP net loss narrowed to $6.2 million from $10.0 million in Q2 2025. Adjusted EBITDA loss improved to $2.8 million from $4.9 million. Operationally, the company launched ECoG Assistant, an AI-based clinical decision support tool leveraging proprietary intracranial EEG data; published 18-month NAUTILUS randomized controlled trial results showing 77% median reduction in generalized tonic-clonic seizures in drug-resistant idiopathic generalized epilepsy; and reached new highs in active prescribers, accounts, and patient pipeline. The company discontinued its DIXI Medical product operations. Management raised full-year 2026 revenue guidance to $99.5–101.5 million (21–23% RNS growth) and upgraded adjusted gross margin guidance to 82.0–83.0%. Preparation for an FDA submission regarding IGE indication expansion remains on track with 24-month NAUTILUS data showing 100% median reduction in seizures among evaluable patients.
Full-year 2026 revenue $99.5M–$101.5M (21–23% RNS growth); adjusted EBITDA loss ($7.5M)–($8.5M)
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The first and only FDA-approved closed-loop brain stimulation device for drug-resistant focal epilepsy. A skull-mounted neurostimulator continuously monitors electrocorticographic activity via implanted cortical leads; when it detects pre-seizure patterns it delivers a brief burst of electrical stimulation to interrupt the ictal event before clinical symptoms emerge. Over several years of use, patients show progressively greater seizure reduction as the device learns individual seizure signatures.
12 patents on file, but none with both an extractable figure and an abstract on Google Patents yet.
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