Co-founded DexCom in 1999 alongside Scott Glenn, John Burd, Lauren Otsuki, and Ellen Preston, building the company that would pioneer continuous glucose monitoring. Prior to DexCom, Megargel earned an MBA from Stanford University (1998) and focused on healthcare venture capital. He was also a co-founder of Avera Pharmaceuticals and held roles at Planet Biopharmaceuticals (Vice President), Windamere Venture Partners, and Mdedge. Megargel passed away in 2021 at age 52.
One of five co-founders of DexCom in 1999 alongside Scott Glenn, John Burd, Lauren Otsuki, and Bret Megargel. Prior to co-founding the continuous glucose monitor company, Preston built a career in medical device and healthcare sales and marketing spanning roughly 30 years, including roles at Johnson & Johnson — where she helped create a new product category and reshape pricing and delivery of contact lenses — and the Arizona Health Sciences Center (AHSC). She studied at Arizona State University. Her background in commercializing paradigm-changing medical products provided the commercial and market-facing expertise that complemented the scientific founders on the early DexCom team.
A biochemist by training (BS, Purdue; MS and PhD, University of...), Burd began his career at Miles Laboratories (Ames) in 1977, developing fluorescent immunoassays for diabetes diagnostics. That work laid the technical foundation for his co-founding DexCom in 1999, where as President and CEO he oversaw development of the first long-term implantable continuous glucose monitor. He holds roughly 35 patents and has authored 40+ publications. Post-DexCom, Burd founded Lysulin (2017), a nutritional supplement company targeting blood sugar management — extending his focus on diabetes beyond sensing into metabolic intervention.
Co-founded DexCom in 1999 alongside Scott Glenn, John Burd, Ellen Preston, and Bret Megargel, serving as a Vice President during the company's early years. Prior to DexCom, Otsuki founded a string of life-sciences ventures including SkinMedica (a clinical skincare company later acquired by Allergan) and Alastin Skincare. She also co-founded Prometheus Biosciences (now Prometheus Biosciences Inc.), NovaCardia, and Oncternal Therapeutics — collectively spanning dermatology, cardiovascular, oncology, and diagnostics. She holds a B.S. from the University of California, Davis. Across two decades, she has founded or co-founded five biotech firms, several of which reached public-market or acquisition exits.
Prior to co-founding DexCom in 1999, Glenn had already founded Prometheus Laboratories (1995) and Santarus (1996), and had been managing partner at Windamere Venture Partners since 1994 — a firm through which he pioneered a venture-company creation model that ultimately produced over two dozen life sciences startups. Earlier ventures included SkinMedica (acquired by Allergan) and, later, Zogenix, Somaxon Pharmaceuticals, and Evoke Pharma. He holds a B.S. from California State University and, after a five-year tenure as DexCom's chairman and founder, stepped away in 2004, well before the G4, G6, and G7 sensors made the company a CGM market leader.