HeartFlow (HTFL) is a publicly traded Imaging & Diagnostics AI company founded in 2007 and based in San Francisco, United States.
No dated funding rounds on file. This company is privately held and may be raising or operating on undisclosed capital.
Heartflow (Nasdaq: HTFL) reported Q2 2026 (quarter ended June 30, 2026) revenue of $64.1 million, up 48% year-over-year from $43.4 million; U.S. revenue was $59.6 million (+51%) and International and other revenue was $4.5 million (+12%). GAAP gross margin was 83.0% versus 75.5% in the prior-year quarter, which the company attributed to higher case volume, U.S. Plaque case volume and production team productivity from AI efficiency initiatives. GAAP loss from operations was $17.9 million (versus $13.7 million a year earlier); GAAP net loss was $15.7 million, or ($0.18) per share. Adjusted EBITDA was ($6.7) million. Cash, cash equivalents and investments totaled $246.8 million at June 30, 2026. Operating expenses rose to $71.1 million (111% of revenue), driven by sales personnel and technology and clinical research investment. The company raised full-year 2026 revenue guidance to $246–$250 million (about 40–42% growth) from $228–$232 million, and raised non-GAAP gross margin guidance to approximately 82% from approximately 81%. The release describes Plaque as an emerging second growth engine alongside FFR CT.
FY2026 revenue $246–$250M (raised from $228–$232M); non-GAAP gross margin ~82% (raised from ~81%)

HeartFlow presents pivotal CT-guided PCI data at the TCT conference.

Randomized P4 trial at TCT 2026 finds CT-guided PCI matches IVUS outcomes; HeartFlow PCI Navigator changes PCI plans in about 70% of patients.

Mayer Brown represents HeartFlow in a patent and trade secrets action over AI-enabled cardiovascular imaging.

HeartFlow targets AI cardiac imaging rival over patents and trade secrets
FFRct Analysis builds a patient-specific 3D model of the coronary arteries from a CT angiography scan and calculates fractional flow reserve to show which narrowings limit blood flow. It is indicated for stenoses between 40% and 90% and received FDA de novo clearance in 2014. It accounted for 98% of HeartFlow's 2025 revenue.
Plaque Analysis uses AI to quantify the volume of coronary plaque and characterize its type in a 3D view, from the same CT scan. The FDA cleared it in October 2022 and cleared a next-generation version in 2025. Category I CPT code 75577 took effect for it on Jan. 1, 2026.
RoadMap Analysis gives readers an anatomic visualization of the coronary arteries from CT images to make scan interpretation more efficient. The FDA cleared it in October 2022, and HeartFlow provides it alongside its other analyses rather than selling it on its own.
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