Calico Life Sciences is an Aging Drug Discovery company founded in 2013 and based in South San Francisco, United States.
No dated funding rounds on file. This company is privately held and may be raising or operating on undisclosed capital.

Revel Pharmaceuticals and Calico publish proof-of-principle in Nature Communications showing an engineered enzyme can remove advanced glycation end products from aged human tissue ex vivo.
Calico's core work is fundamental research into the biology of aging combined with drug discovery aimed at age-related diseases such as neurodegeneration and cancer. The organization pairs deep biological investigation, including computational and model-organism studies of why organisms age, with a translational pipeline that moves promising targets toward therapeutics. Backed by Alphabet's long-horizon capital, Calico is structured to pursue high-risk, long-timeline aging science that conventional biotech funding cycles typically cannot support.
Through its 2014 collaboration with AbbVie, Calico built a pipeline of more than 20 early-stage programs spanning immuno-oncology and neurodegeneration, advancing three candidates into clinical trials. After AbbVie exited the partnership in November 2025 following the Phase II/III failure of an ALS candidate (fosigotifator), Calico retains assets and continues developing therapies as an Alphabet-backed entity. The pipeline reflects Calico's strategy of converting aging-biology insights into concrete drug candidates for diseases of later life.
1 patent on file, but none with both an extractable figure and an abstract on Google Patents yet.
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