Cambrian Biopharma is an Aging Drug Discovery company founded in 2019 and based in New York, United States. It has raised $200M in total funding, most recently a Series C in 2021.
| Date | Stage | Amount | Valuation | Lead investors |
|---|---|---|---|---|
| Oct 19, 2021 | Series C | $100M | — | Anthos Capital, SALT Fund |
Cambrian operates as a Distributed Development Company, building and financing a portfolio of affiliate biotechs that each target a biological driver of aging. By spreading capital and risk across many independently run programs rather than betting on a single asset, the model aims to reduce the failure risk of conventional asset-centric startups while sharing operational infrastructure, scientific advisory resources, and capital-raising support. The structure lets Cambrian advance a broad set of healthspan-extending therapeutics in parallel and spin affiliates toward partnerships or public offerings.
Cambrian's pipeline spans multiple clinical-stage and preclinical programs run through affiliate companies, including Amplifier Therapeutics (a peripherally restricted pan-AMPK activator for cardiometabolic disease), Tornado Therapeutics (next-generation mTOR inhibitors for healthspan), and Telos Biotech (enhancing cell therapies against senescence and exhaustion). Each program targets a distinct hallmark or driver of aging with the goal of treating and preventing age-related diseases. As of late 2025 the portfolio included several affiliates with multiple assets in clinical trials.