Insilico Medicine (HKEX: 03696) is a publicly traded Aging Drug Discovery company founded in 2014 and based in Hong Kong, Hong Kong.
| Date | Stage | Amount | Valuation | Lead investors |
|---|---|---|---|---|
| Dec 30, 2025 | IPO (HKEX: 2179) | $293M | $1.7B | Tencent, Eli Lilly |
| Mar 14, 2025 | Series E | $110M | — |
| Value Partners Group |
| Jun 8, 2022 | Series D | $60M | — | Warburg Pincus |

Insilico nominates ISM1354, an AI-designed GIPR blocker for obesity, showing 18x better exposure than a comparison compound in preclinical data.

ARDD 2026 opens at Harvard with Big Pharma and regulators in attendance, as speakers call for clinical rigor in the longevity field.

Insilico Medicine launches a research program using AI, circular mRNA, and in vivo T-cell engineering to target aging cells as "longevity vaccines."

Insilico Medicine's AI-designed lung fibrosis drug rentosertib showed younger blood-protein profiles on six aging clocks in a Phase 2a trial.

Six proteomic clocks detect a younger biological age signal from Insilico's rentosertib in a Phase 2a IPF trial, published in Nature Biotechnology.
Pharma.AI is Insilico Medicine's end-to-end generative-AI drug discovery platform, spanning target identification (PandaOmics), generative chemistry for novel molecule design (Chemistry42), and clinical-trial outcome prediction (inClinico). The platform connects biology, chemistry, and clinical data to nominate disease targets and design drug candidates faster and at lower cost than conventional methods. It underpins Insilico's internal pipeline of clinical- and preclinical-stage programs and is also offered to pharmaceutical partners, and is paired with an automated, robotics-driven laboratory for experimental validation.
Insilico advances a pipeline of clinical- and preclinical-stage drug candidates discovered and designed using its generative-AI platform, with its lead programs aimed at fibrosis, oncology, and other age- and disease-related conditions. Several candidates have entered clinical trials, validating the AI-first discovery approach. Proceeds from the company's 2025 Hong Kong IPO are earmarked largely for advancing these clinical-stage candidates and for expanding early-stage discovery, new generative-AI models, and its automated laboratory.
17 patents on file, but none with both an extractable figure and an abstract on Google Patents yet.