Vandria is an Aging Drug Discovery company founded in 2021 and based in Plan-les-Ouates, Switzerland. It has raised $32M in total funding, most recently a Series A.

Vandria's Phase 1 data on VNA-318, a mitophagy-targeting Alzheimer's candidate, shows it is safe and well-tolerated in humans at AAIC 2025.
VNA-318 is Vandria's lead clinical candidate, a small molecule designed to induce mitophagy, the selective removal of damaged mitochondria, so cells can restore healthy energy production and lower chronic inflammation. The company describes a dual mode of action combining immediate cognitive benefit with long-term disease modification, and has advanced VNA-318 into a first-in-human Phase 1 trial. Target indications span mild cognitive impairment, Alzheimer's disease, Parkinson's disease and major depressive disorder, with potential extension to non-central-nervous-system conditions affecting muscle, liver and lung, reflecting the broad role of mitochondrial dysfunction in aging.
3 patents on file, but none with both an extractable figure and an abstract on Google Patents yet.