Scribe Therapeutics is a Gene & Genome Editing Platforms company founded in 2018 and based in Alameda, United States. It has raised $120M in total funding, most recently a Series B in 2021.
| Date | Stage | Amount | Valuation | Lead investors |
|---|---|---|---|---|
| Mar 1, 2021 | Series B | $100M | — | Avoro Ventures, OrbiMed |
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Scribe's core technology, also called X-Editor, designs novel CRISPR enzymes from scratch through directed molecular engineering rather than adopting wild-type Cas9 or Cas12. The resulting editors are optimized across multiple axes — specificity, on-target activity, and small size for easier delivery via lipid nanoparticles or viral vectors. The platform is licensed to pharmaceutical partners as the editing engine behind their in vivo genetic-medicine programs; Sanofi has used XE-derived enzymes for both ex vivo cell therapies and in vivo programs targeting sickle cell disease and other genomic conditions.
7 patents on file, but none with both an extractable figure and an abstract on Google Patents yet.
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