Ranked by total raised · 25 of 40 on the roster
Largest US-regulated crypto exchange and custodian; operator of Base, an Ethereum L2 that has become a major stablecoin settlement layer.
Institutional-focused digital asset exchange led by former NYSE president Tom Farley; owner of crypto news outlet CoinDesk and the first crypto exchange to list on the NYSE.
Issues USD Coin (USDC) and Euro Coin (EURC), the world's second-largest regulated stablecoins, and operates a global payments network for on-chain settlement.
22 more companies in this ranking, plus every other sort, every roster row, and the full analytical layer behind each profile.
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Veteran US cryptocurrency exchange expanding into tokenized equities, derivatives, and its own Ink Layer-2, widely expected to pursue an IPO.
MPC-based digital-asset custody and treasury infrastructure for institutions moving, storing, and issuing crypto.
Winklevoss-founded, New York-regulated crypto exchange and custodian, issuer of the Gemini dollar (GUSD), now publicly listed on Nasdaq.
Web3 payments infrastructure company providing fiat-to-crypto on/off-ramp solutions used by hundreds of wallets and apps, plus NFT checkout and merchant tools.
Ethereum software company behind the MetaMask self-custody wallet, the Infura node/API infrastructure, and the Linea zkEVM Layer 2.
Federally chartered digital-asset bank offering institutional crypto custody, settlement, and stablecoin issuance.
Developer of Avalanche, a Layer 1 network of customizable, independently scalable subnets (now called L1s).
Maker of hardware self-custody wallets, paired with the Ledger Live app and enterprise custody services for institutions.
Web3 developer platform providing node and data APIs, a rollup-as-a-service stack, and account-abstraction wallet tooling.
Blockchain analytics platform used by governments, exchanges and financial institutions for compliance and investigations.
Regulated blockchain infrastructure company that issues USDP, PAX Gold, and powers white-label stablecoins including PayPal's PYUSD.
Creator of ZKsync, a zero-knowledge rollup scaling Ethereum, and the Elastic Network of interoperable ZK chains.
Web3 gaming platform that operates Immutable zkEVM, a gaming-focused Ethereum Layer-2, and the IMX token.
Builder of the Polygon Ethereum-scaling ecosystem — the Polygon PoS chain, zkEVM, and the AggLayer cross-chain settlement layer.
Largest NFT marketplace, relaunched in 2025 as the multichain OS2 trading platform; its planned SEA token was delayed indefinitely in March 2026.
Institutional digital-asset custody and prime-brokerage provider; listed on the NYSE after a January 2026 IPO.
Developer of Aptos, a high-throughput Layer 1 blockchain built on the Move language by former members of Meta's Diem team.
Creator of Sui, an object-centric Layer 1 blockchain written in the Move programming language by a team out of Meta's Diem project.
Leading multichain self-custody wallet, Solana-first, with 10M+ monthly active users across Solana, Ethereum, Polygon, and Bitcoin.
Developer of Monad, a parallel-execution, fully EVM-compatible Layer 1 blockchain that launched mainnet in November 2025.
Builds modular, permissionless on-chain lending infrastructure that powers products like Coinbase's crypto-backed loans.
Crypto AML, wallet-screening and blockchain analytics provider for banks, fintechs and law enforcement.